Difference between revisions of "Dna synthesizer"

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Biology Team's Pilot Project
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#REDIRECT [[DNA Synthesizer]]
 
 
==SSI Bio 2016 Pilot Project==
 
SSI Bio is launching with the DNA synthesizer as their primary project.
 
 
 
==Components of the Synthesis Project==
 
SSI Bio will be breaking up this DNA synthesizer project into several smaller subteams to tackle the several different systems needed
 
 
 
===Enzymatic Synthesis Chemistry===
 
 
 
===Safe Phosphoramidite Chemistry===
 
A more conventional alternative to aiming for enzymatic synthesis would be to try to adjust conventional phosphoramidite chemistry to be safer for use in space. This might involve creating a system that can synthesize DNA using safer organic solvents and less toxic reagents.
 
 
 
===Microfluidic Synthesizer Design===
 
 
 
===Reassembly Chemistry and Algorithm===
 
 
 
===DNA Product Verification===
 
 
 
====Overview====
 
Once a strand of DNA is made, we will need to check to make sure that it is the correct desired sequence.
 
==Effects of limits of Space on Synthesizer==
 
 
 
===Payload Size and Power constraints===
 
We'd like to fit our synthesizer into a 10 centimeter cube, so that it could be launched on a [https://en.wikipedia.org/wiki/CubeSat CubeSat] or another standardized research payload.
 
 
 
===What kind of shielding do we need?===
 
We're not sure what kind of shielding we need! UV radiation can have damage DNA through a process called [https://en.wikipedia.org/wiki/Direct_DNA_damage Direct DNA damage] that can lead to thymine or pyrimidine dimers. This is what causes sunburn, and it's why your skin can tan to help block out UVB.
 
 
 
====Communication from Device====
 
Depending on our strategy for launching to space, communication from our device to some sort of receiver we can listen to involves a number of interesting questions. How do we return the message that synthesis has been carried out successfully? Will the message describe the sequence of the product created, or a simple boolean yes or no?
 
 
 
==History of DNA synthesizer idea in SSI==
 
The idea of a DNA synthesizer for space has been floating around SSI for some time. [[John Cumbers - Synthetic Biology | One of the earliest recordings stretches back to 2013, in a talk given John Cumbers.]] John Cumbers was also consulted during the initial conception and planning of the project in the summer of 2015.
 

Latest revision as of 07:57, 18 September 2017

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