Difference between revisions of "Dna synthesizer"

Latest revision as of 07:57, 18 September 2017

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DNA Synthesizer

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-Biology Team's Pilot Project
+#REDIRECT [[DNA Synthesizer]]
-==SSI Bio 2016 Pilot Project==
-SSI Bio is launching with the DNA synthesizer as their primary project.
-==Components of the Synthesis Project==
-SSI Bio will be breaking up this DNA synthesizer project into several smaller subteams to tackle the several different systems needed
-===Enzymatic Synthesis Chemistry===
-===Safe Phosphoramidite Chemistry===
-A more conventional alternative to aiming for enzymatic synthesis would be to try to adjust conventional phosphoramidite chemistry to be safer for use in space. This might involve creating a system that can synthesize DNA using safer organic solvents and less toxic reagents.
-===Microfluidic Synthesizer Design===
-===Reassembly Chemistry and Algorithm===
-===DNA Product Verification===
-Once a strand of DNA is made, we will need to check to make sure that it is the correct desired sequence.
-==Effects of Space on Synthesizer==
-===Payload Size and Power constraints===
-We'd like to fit our synthesizer into a 10 centimeter cube, so that it could be launched on a [https://en.wikipedia.org/wiki/CubeSat CubeSat] or another standardized research payload.
-===What kind of shielding do we need?===
-We're not sure what kind of shielding we need! UV radiation can have damage DNA through a process called [https://en.wikipedia.org/wiki/Direct_DNA_damage Direct DNA damage] that can lead to thymine or pyrimidine dimers. This is what causes sunburn, and it's why your skin can tan to help block out UVB.
-====Communication from Device====
-Depending on our strategy for launching to space, communication from our device to some sort of receiver we can listen to involves a number of interesting questions. How do we return the message that synthesis has been carried out successfully? Will the message describe the sequence of the product created, or a simple boolean yes or no?
-==History of DNA synthesizer idea in SSI==
-The idea of a DNA synthesizer for space has been floating around SSI for some time. [[John Cumbers - Synthetic Biology | One of the earliest recordings stretches back to 2013, in a talk given John Cumbers.]] John Cumbers was also consulted during the initial conception and planning of the project in the summer of 2015.

Difference between revisions of "Dna synthesizer"

Latest revision as of 07:57, 18 September 2017

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